Weâve blogged before about erythritol, a sugar alcohol thatâs become increasingly popular and, like xylitol, may offer some protection against tooth decay and gum disease by controlling harmful bacteria.
Because itâs a zero-calorie sweetener that doesnât seem to affect blood glucose levels, itâs become especially popular in both food and drink for those who want or need to watch their sugar intake. The side effects you usually hear about are the ones that apply to other sugar alcohols: If you eat too much, your gut may complain – a lot.
But recently, other potential side effects have emerged that are far more concerning, especially since many who regularly consume erythritol-sweetened products, such as people with diabetes, are already at higher risk for the conditions: heart attack and stroke.
This emerged from a paper published a few weeks ago in Nature Medicine. Its authors studied the blood of more than 4000 patients, looking for anything that might raise the risk of a major cardiac event. Erythritol levels in the blood were just that sign. More of it in the blood meant a higher risk of heart attack and stroke.
Taking it a step further, the researchers gave erythritol to animal models. They saw enhanced clot formation in models of arterial disease. They added erythritol to blood outside of the body. And found that adding erythritol to blood made it âclump up,â or form a blood clot by activating platelets.
Platelets are the tiny components in your blood that rush to the site of an injury to stop us from bleeding. That keeps you from bleeding out. But when theyâre activated within our bodies, they cause blood clots, which can lead to heart attacks and strokes.
âA serving of erythritol in common âketo-friendlyâ processed food products made blood levels of erythritol go up 1,000-fold, well above the levels linked to enhanced clotting risks,â [lead author] Dr. [Stanley] Hazen states. âWe found that the risk for clotting can be increased for several days after consumption of just one serving of artificially sweetened food containing erythritol.â
âIt wasnât a modest effect,â added Dr. Hazen. âIt was a very large effect that we were seeing reproduced across multiple groups and across geographies.â And while the study doesnât prove causality, it certainly gives cause for concern.
More research needs to be done to confirm or disprove these findings. Perhaps itâs not erythritol itself but something in how it is processed or that itâs most often made from GMO corn or some other factor. At this point, we just donât know.
If you choose to use or consume erythritol, it may be wise to choose only non-GMO products or those marked as USDA Organic. But if itâs sweetness youâre after, there are alternatives such as stevia and monk fruit. Both of these are zero-calorie and have no impact on blood glucose. Just be sure to read the labels closely to make sure no GMO erythritol has been added, as it sometimes is with these other alternative sweeteners.
And consider reducing your intake of ultra-processed foods in general. Theyâre no friend to your health. Opt for real food, and youâll not only avoid ingredients that your body was never designed to consume; youâll get more of a nutritional punch from whole foods and meals you cook yourself.
More on erythritol and other alternative sweeteners from Dr. Axe